Class b: All beta proteins [48724] (180 folds) |
Fold b.50: Acid proteases [50629] (1 superfamily) barrel, closed; n=6, S=10, complex topology |
Superfamily b.50.1: Acid proteases [50630] (4 families) |
Family b.50.1.2: Pepsin-like [50646] (11 proteins) duplication: consists of two similar barrel domains N-terminal: barrel, partly opened; n*=6, S*=10 |
Protein beta-secretase (memapsin) [50671] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [50672] (329 PDB entries) Uniprot P56817 58-446 ! Uniprot P56817 60-447 |
Domain d1xn2c_: 1xn2 C: [122180] automated match to d1fkna_ |
PDB Entry: 1xn2 (more details), 1.9 Å
SCOPe Domain Sequences for d1xn2c_:
Sequence; same for both SEQRES and ATOM records: (download)
>d1xn2c_ b.50.1.2 (C:) beta-secretase (memapsin) {Human (Homo sapiens) [TaxId: 9606]} gsfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrql sstyrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnwe gilglayaeiarpddslepffdslvkqthvpnlfslqlcgagfplnqsevlasvggsmii ggidhslytgslwytpirrewyyeviivrveingqdlkmdckeynydksivdsgttnlrl pkkvfeaavksikaasstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnqsf ritilpqqylrpvedvatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigfav sachvhdefrtaavegpfvtldmedcgyn
Timeline for d1xn2c_: