SCOP 1.73: Domain d1xlwa1: 1xlw A:4-529

Lineage for d1xlwa1 (1xlw A:4-529)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (35 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (5 proteins)

6. Protein Butyryl cholinesterase [102612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102613] (7 PDB entries)

8. Domain d1xlwa1: 1xlw A:4-529 [122139]
   automatically matched to d1p0ia_
   complexed with cl, dep, fuc, ful, gol, nag, s, so4; mutant

Details for d1xlwa1

PDB Entry: 1xlw, 2.1 Å

PDB Description: diethylphosphorylated butyrylcholinesterase (nonaged) obtained by reaction with echothiophate

PDB Compounds: (A:) butyrylcholinesterase

SCOP Domain Sequences for d1xlwa1:

Sequence, based on SEQRES records:

>d1xlwa1 c.69.1.1 (A:4-529) Butyryl cholinesterase {Human (Homo sapiens) [TaxId: 9606]}
iiiatkngkvrgmqltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfeh
rssklpwpewmgvmhgyeiefvfglplerrdqytkaeeilsrsivkrwanfakygnpqet
qnqstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv

Sequence, based on observed residues (ATOM records):

>d1xlwa1 c.69.1.1 (A:4-529) Butyryl cholinesterase {Human (Homo sapiens) [TaxId: 9606]}
iiiatkngkvrgmqltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkyan
sccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgts
slhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqknia
afggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnrt
lnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdmp
dillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvse
fgkesilfhytdwvqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfehrs
sklpwpewmgvmhgyeiefvfglplerrdqytkaeeilsrsivkrwanfakygnpqetqn
qstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv

Timeline for d1xlwa1:

• d1xlwa1 is new in SCOP 1.73
  
• d1xlwa1 appears in SCOP 1.75
  
• d1xlwa1 appears in the current release, SCOPe 2.08, called d1xlwa_