Lineage for d1xdmz_ (1xdm Z:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2826025Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2834402Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 2834403Family c.1.10.1: Class I aldolase [51570] (13 proteins)
    the catalytic lysine forms schiff-base intermediate with substrate
    possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels
  6. 2834647Protein Fructose-1,6-bisphosphate aldolase [51576] (11 species)
  7. 2834653Species Human (Homo sapiens) [TaxId:9606] [254964] (6 PDB entries)
  8. 2834669Domain d1xdmz_: 1xdm Z: [121887]
    automated match to d1fdja_
    complexed with so4

Details for d1xdmz_

PDB Entry: 1xdm (more details), 3 Å

PDB Description: structure of human aldolase b associated with hereditary fructose intolerance (a149p), at 291k
PDB Compounds: (Z:) Fructose-bisphosphate aldolase B

SCOPe Domain Sequences for d1xdmz_:

Sequence, based on SEQRES records: (download)

>d1xdmz_ c.1.10.1 (Z:) Fructose-1,6-bisphosphate aldolase {Human (Homo sapiens) [TaxId: 9606]}
paltqeqkkelseiaqsivangkgilaadesvgtmgnrlqrikventeenrrqfreilfs
vdssinqsiggvilfhetlyqkdsqgklfrnilkekgivvgikldqggaplagtnketti
qgldglsercaqykkdgvdfgkwrpvlriadqcpsslaiqenanalaryasicqqnglvp
ivepevipdgdhdlehcqyvtekvlaavykalndhhvylegtllkpnmvtaghactkkyt
peqvamatvtalhrtvpaavpgicflsggmseedatlnlnainlcplpkpwklsfsygra
lqasalaawggkaankeatqeafmkramancqaakgqy

Sequence, based on observed residues (ATOM records): (download)

>d1xdmz_ c.1.10.1 (Z:) Fructose-1,6-bisphosphate aldolase {Human (Homo sapiens) [TaxId: 9606]}
paltqeqkkelseiaqsivangkgilaadesvgtmgnrlqrikventeenrrqfreilfs
vdssinqsiggvilfhetlyqkdsqgklfrnilkekgivvgiklddglsercaqykkdgv
dfgkwrsslaiqenanalaryasicqqnglvpivepedlehcqyvtekvlaavykalndh
hvylegtllkpnmvtytpeqvamatvtalhrtvpaavpgicflsggmseedatlnlnain
lcplpkpwklsfsygralqasalaawggkaankeatqeafmkramancqaakgqy

SCOPe Domain Coordinates for d1xdmz_:

Click to download the PDB-style file with coordinates for d1xdmz_.
(The format of our PDB-style files is described here.)

Timeline for d1xdmz_: