Lineage for d1xdla1 (1xdl A:6-343)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2434695Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2443024Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 2443025Family c.1.10.1: Class I aldolase [51570] (13 proteins)
    the catalytic lysine forms schiff-base intermediate with substrate
    possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels
  6. 2443269Protein Fructose-1,6-bisphosphate aldolase [51576] (11 species)
  7. 2443293Species Human (Homo sapiens), liver isozyme [TaxId:9606] [51578] (2 PDB entries)
  8. 2443312Domain d1xdla1: 1xdl A:6-343 [121872]
    complexed with so4

Details for d1xdla1

PDB Entry: 1xdl (more details), 3 Å

PDB Description: structure of human aldolase b associated with hereditary fructose intolerance (a149p), at 277k
PDB Compounds: (A:) Fructose-bisphosphate aldolase B

SCOPe Domain Sequences for d1xdla1:

Sequence, based on SEQRES records: (download)

>d1xdla1 c.1.10.1 (A:6-343) Fructose-1,6-bisphosphate aldolase {Human (Homo sapiens), liver isozyme [TaxId: 9606]}
altqeqkkelseiaqsivangkgilaadesvgtmgnrlqrikventeenrrqfreilfsv
dssinqsiggvilfhetlyqkdsqgklfrnilkekgivvgikldqggaplagtnkettiq
gldglsercaqykkdgvdfgkwrpvlriadqcpsslaiqenanalaryasicqqnglvpi
vepevipdgdhdlehcqyvtekvlaavykalndhhvylegtllkpnmvtaghactkkytp
eqvamatvtalhrtvpaavpgicflsggmseedatlnlnainlcplpkpwklsfsygral
qasalaawggkaankeatqeafmkramancqaakgqyv

Sequence, based on observed residues (ATOM records): (download)

>d1xdla1 c.1.10.1 (A:6-343) Fructose-1,6-bisphosphate aldolase {Human (Homo sapiens), liver isozyme [TaxId: 9606]}
altqeqkkelseiaqsivangkgilaadesvgtmgnrlqrikventeenrrqfreilfsv
dssinqsiggvilfhetlyqkdsqgklfrnilkekgivvgikldqgldglsercaqykkd
gvdfgkwrpvlrsslaiqenanalaryasicqqnglvpivepevipehcqyvtekvlaav
ykalndhhvylegtllkpnmvtytpeqvamatvtalhrtvpaavpgicflsggmseedat
lnlnainlcplpkpwklsfsygralqasalaawggkaankeatqeafmkramancqaakg
qyv

SCOPe Domain Coordinates for d1xdla1:

Click to download the PDB-style file with coordinates for d1xdla1.
(The format of our PDB-style files is described here.)

Timeline for d1xdla1: