SCOPe 2.08: Domain d1x74a1: 1x74 A:2-360

Lineage for d1x74a1 (1x74 A:2-360)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.123: CoA-transferase family III (CaiB/BaiF) [89795] (1 superfamily)
   consist of two different alpha/beta domains; N-terminal domain has a SurE-like topology with a left-handed beta-alpha-beta unit

4. Superfamily c.123.1: CoA-transferase family III (CaiB/BaiF) [89796] (2 families)

5. Family c.123.1.1: CoA-transferase family III (CaiB/BaiF) [89797] (5 proteins)
   forms interlocked homodimer of two ring-like subunits

6. Protein 2-methylacyl-CoA racemase Mcr [142827] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [142828] (7 PDB entries)
   Uniprot O06543 2-360

8. Domain d1x74a1: 1x74 A:2-360 [121771]
   Other proteins in same PDB: d1x74b_, d1x74c_, d1x74d_
   complexed with gol, po4; mutant

Details for d1x74a1

PDB Entry: 1x74, 1.79 Å

PDB Description: alpha-methylacyl-coa racemase from mycobacterium tuberculosis- mutational and structural characterization of the fold and active site

PDB Compounds: (A:) 2-methylacyl-CoA racemase

SCOPe Domain Sequences for d1x74a1:

Sequence, based on SEQRES records:

>d1x74a1 c.123.1.1 (A:2-360) 2-methylacyl-CoA racemase Mcr {Mycobacterium tuberculosis [TaxId: 1773]}
agplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtadl
ksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprs
qqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkg
qvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaie
pqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpv
lafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

Sequence, based on observed residues (ATOM records):

>d1x74a1 c.123.1.1 (A:2-360) 2-methylacyl-CoA racemase Mcr {Mycobacterium tuberculosis [TaxId: 1773]}
agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

Timeline for d1x74a1:

• d1x74a1 first appeared in SCOP 1.73
  
• d1x74a1 appears in SCOPe 2.07