Lineage for d1x74a1 (1x74 A:2-360)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2150853Fold c.123: CoA-transferase family III (CaiB/BaiF) [89795] (1 superfamily)
    consist of two different alpha/beta domains; N-terminal domain has a SurE-like topology with a left-handed beta-alpha-beta unit
  4. 2150854Superfamily c.123.1: CoA-transferase family III (CaiB/BaiF) [89796] (2 families) (S)
  5. 2150855Family c.123.1.1: CoA-transferase family III (CaiB/BaiF) [89797] (5 protein domains)
    forms interlocked homodimer of two ring-like subunits
  6. 2150856Protein 2-methylacyl-CoA racemase Mcr [142827] (1 species)
  7. 2150857Species Mycobacterium tuberculosis [TaxId:1773] [142828] (7 PDB entries)
    Uniprot O06543 2-360
  8. 2150865Domain d1x74a1: 1x74 A:2-360 [121771]
    Other proteins in same PDB: d1x74b_, d1x74c_, d1x74d_
    complexed with gol, po4; mutant

Details for d1x74a1

PDB Entry: 1x74 (more details), 1.79 Å

PDB Description: alpha-methylacyl-coa racemase from mycobacterium tuberculosis- mutational and structural characterization of the fold and active site
PDB Compounds: (A:) 2-methylacyl-CoA racemase

SCOPe Domain Sequences for d1x74a1:

Sequence, based on SEQRES records: (download)

>d1x74a1 c.123.1.1 (A:2-360) 2-methylacyl-CoA racemase Mcr {Mycobacterium tuberculosis [TaxId: 1773]}
agplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtadl
ksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprs
qqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkg
qvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaie
pqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpv
lafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

Sequence, based on observed residues (ATOM records): (download)

>d1x74a1 c.123.1.1 (A:2-360) 2-methylacyl-CoA racemase Mcr {Mycobacterium tuberculosis [TaxId: 1773]}
agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

SCOPe Domain Coordinates for d1x74a1:

Click to download the PDB-style file with coordinates for d1x74a1.
(The format of our PDB-style files is described here.)

Timeline for d1x74a1: