SCOPe 2.06: Domain d1x3sa1: 1x3s A:2-178

Lineage for d1x3sa1 (1x3s A:2-178)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rab18 [142233] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142234] (1 PDB entry)
   Uniprot Q9NP72 2-178

8. Domain d1x3sa1: 1x3s A:2-178 [121670]
   complexed with gnp, mg

Details for d1x3sa1

PDB Entry: 1x3s, 1.32 Å

PDB Description: Crystal structure of human Rab18 in complex with Gppnhp

PDB Compounds: (A:) Ras-related protein Rab-18

SCOPe Domain Sequences for d1x3sa1:

Sequence; same for both SEQRES and ATOM records:

>d1x3sa1 c.37.1.8 (A:2-178) Rab18 {Human (Homo sapiens) [TaxId: 9606]}
dedvlttlkiliigesgvgksslllrftddtfdpelaatigvdfkvktisvdgnkaklai
wdtagqerfrtltpsyyrgaqgvilvydvtrrdtfvkldnwlneletyctrndivnmlvg
nkidkenrevdrneglkfarkhsmlfieasaktcdgvqcafeelvekiiqtpglwes

Timeline for d1x3sa1:

• d1x3sa1 first appeared in SCOP 1.73
  
• d1x3sa1 appears in SCOPe 2.05
  
• d1x3sa1 appears in SCOPe 2.07
  
• d1x3sa1 appears in the current release, SCOPe 2.08