SCOPe 2.06: Domain d1wxaa1: 1wxa A:8-110

Lineage for d1wxaa1 (1wxa A:8-110)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
   core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

4. Superfamily d.15.1: Ubiquitin-like [54236] (11 families)

5. Family d.15.1.5: Ras-binding domain, RBD [54263] (14 proteins)
   contains Pfam PF00788 and Pfam PF02196

6. Protein Afadin [142964] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [142965] (1 PDB entry)
   Uniprot Q9QZQ1 246-348
   The FHA domain structure is also known (PDB 1wln)

8. Domain d1wxaa1: 1wxa A:8-110 [121395]
   Other proteins in same PDB: d1wxaa2, d1wxaa3

Details for d1wxaa1

PDB Entry: 1wxa

PDB Description: solution structure of ras-binding domain in mouse af-6 protein

PDB Compounds: (A:) Afadin

SCOPe Domain Sequences for d1wxaa1:

Sequence; same for both SEQRES and ATOM records:

>d1wxaa1 d.15.1.5 (A:8-110) Afadin {Mouse (Mus musculus) [TaxId: 10090]}
sggtlriyadslkpnipyktillsttdtadfavaeslekyglekenpkdyciarvmlppg
aqhsdergakeiildddecplqifrewpsdkgilvfqlkrrpp

Timeline for d1wxaa1:

• d1wxaa1 first appeared in SCOP 1.73
  
• d1wxaa1 appears in SCOPe 2.05
  
• d1wxaa1 appears in SCOPe 2.07
  
• d1wxaa1 appears in the current release, SCOPe 2.08