Lineage for d1wp4c2 (1wp4 C:2-157)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2844998Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (19 proteins)
    the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
    C-terminal domains also show some similarity
  6. 2845080Protein Hydroxyisobutyrate dehydrogenase [102171] (4 species)
  7. 2845089Species Thermus thermophilus [TaxId:274] [102172] (2 PDB entries)
    structural genomics
  8. 2845096Domain d1wp4c2: 1wp4 C:2-157 [121140]
    Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
    automatically matched to d1j3vc2
    complexed with ndp, so4

Details for d1wp4c2

PDB Entry: 1wp4 (more details), 2 Å

PDB Description: Structure of TT368 protein from Thermus Thermophilus HB8
PDB Compounds: (C:) 3-hydroxyisobutyrate dehydrogenase

SCOPe Domain Sequences for d1wp4c2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1wp4c2 c.2.1.6 (C:2-157) Hydroxyisobutyrate dehydrogenase {Thermus thermophilus [TaxId: 274]}
ekvafiglgamgypmaghlarrfptlvwnrtfekalrhqeefgseavplervaearvift
clpttrevyevaealypylregtywvdatsgepeasrrlaerlrekgvtyldapvsggts
gaeagtltvmlggpeeavervrpflayakkvvhvgp

SCOPe Domain Coordinates for d1wp4c2:

Click to download the PDB-style file with coordinates for d1wp4c2.
(The format of our PDB-style files is described here.)

Timeline for d1wp4c2: