SCOPe 2.08: Domain d1wntc_: 1wnt C:

Lineage for d1wntc_ (1wnt C:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein automated matches [190085] (59 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186828] (21 PDB entries)

8. Domain d1wntc_: 1wnt C: [121104]
   automated match to d1pr9a_
   complexed with nap

Details for d1wntc_

PDB Entry: 1wnt, 2.3 Å

PDB Description: structure of the tetrameric form of human l-xylulose reductase

PDB Compounds: (C:) L-xylulose reductase

SCOPe Domain Sequences for d1wntc_:

Sequence; same for both SEQRES and ATOM records:

>d1wntc_ c.2.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
melflagrrvlvtgagkgigrgtvqalhatgarvvavsrtqadldslvrecpgiepvcvd
lgdweateralgsvgpvdllvnnaavallqpflevtkeafdrsfevnlraviqvsqivar
gliargvpgaivnvssqcsqravtnhsvycstkgaldmltkvmalelgphkirvnavnpt
vvmtsmgqatwsdphkaktmlnriplgkfaevehvvnailfllsdrsgmttgstlpvegg
fwac

Timeline for d1wntc_:

• d1wntc_ first appeared in SCOP 1.73, called d1wntc1
  
• d1wntc_ appears in SCOPe 2.07