SCOPe 2.07: Domain d1wn7a2: 1wn7 A:348-756

Lineage for d1wn7a2 (1wn7 A:348-756)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)

6. Protein Family B DNA polymerase [56680] (7 species)

7. Species Pyrococcus kodakaraensis [TaxId:311400] [56685] (2 PDB entries)
   Uniprot P56689 1-758 # 93% sequence identity; Thermococcus kodakarensis KOD1 TaxID: 69014

8. Domain d1wn7a2: 1wn7 A:348-756 [121089]
   Other proteins in same PDB: d1wn7a1
   complexed with gol, ni; mutant

Details for d1wn7a2

PDB Entry: 1wn7, 2.75 Å

PDB Description: Crystal structure of archaeal family B DNA polymerase mutant

PDB Compounds: (A:) Family B DNA Polymerase

SCOPe Domain Sequences for d1wn7a2:

Sequence, based on SEQRES records:

>d1wn7a2 e.8.1.1 (A:348-756) Family B DNA polymerase {Pyrococcus kodakaraensis [TaxId: 311400]}
stgnlvewfllrkayernelapnkpdekelarrrqsyeggyvkeperglwenivyldfrs
lypsiiithnvspdtlnregckeydvapqvghrfckdfpgfipsllgdlleerqkikkkm
katidpierklldyrqraikilansyygyygyararwyckecaesvtawgreyitmtike
ieekygfkviysdtdgffatipgadaetvkkkameflkyinaklpgaleleyegfyergf
fvtkkkyavideegkittrgleivrrdwseiaketqarvleallkdgdvekavrivkevt
eklskyevppeklviheqitrdlkdykatgphvavakrlaargvkirpgtvisyivlkgs
grigdraipfdefdptkhkydaeyyienqvlpaverilrafgyrkedlr

Sequence, based on observed residues (ATOM records):

>d1wn7a2 e.8.1.1 (A:348-756) Family B DNA polymerase {Pyrococcus kodakaraensis [TaxId: 311400]}
stgnlvewfllrkayernelapnkpdekelarrrqsyeggyvkeperglwenivyldfrs
lypsiiithnvspdtlnregckeydvapqvghrfckdfpgfipsllgdlleerqkikkkm
katidpierklldyrqraikilansyygyygyararwyckecaesvtawgreyitmtike
ieekygfkviysdtdgffatipgadaetvkkkameflkyinaklpgaleleyegfyergf
fvtkkkyavideegkittrgleivrrdwseiaketqarvleallkdgdvekavrivkevt
eklskyevppeklviheqiphvavakrlaatvisyivlraipfdefdptkhkydaeyyie
nqvlpaverilrafgyrkedlr

Timeline for d1wn7a2:

• d1wn7a2 first appeared in SCOP 1.73
  
• d1wn7a2 appears in SCOPe 2.06
  
• d1wn7a2 appears in the current release, SCOPe 2.08