SCOP 1.73: Domain d1w82a1: 1w82 A:5-352

Lineage for d1w82a1 (1w82 A:5-352)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase p38 [56129] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56130] (41 PDB entries)

8. Domain d1w82a1: 1w82 A:5-352 [120709]
   automatically matched to d1a9u__
   complexed with l10

Details for d1w82a1

PDB Entry: 1w82, 2.2 Å

PDB Description: p38 kinase crystal structure in complex with small molecule inhibitor

PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOP Domain Sequences for d1w82a1:

Sequence; same for both SEQRES and ATOM records:

>d1w82a1 d.144.1.7 (A:5-352) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltd
dhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyva
trwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpga
ellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqala
hayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvppp

Timeline for d1w82a1:

• d1w82a1 is new in SCOP 1.73
  
• d1w82a1 appears in SCOP 1.75
  
• d1w82a1 appears in the current release, SCOPe 2.08, called d1w82a_