SCOPe 2.02: Domain d1w2kh1: 1w2k H:16-257

Lineage for d1w2kh1 (1w2k H:16-257)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (33 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d1w2kh1: 1w2k H:16-257 [120584]
   Other proteins in same PDB: d1w2kl1, d1w2kl2, d1w2kl3, d1w2kt1, d1w2kt2
   automatically matched to d1cvwh_
   complexed with 380, bgc, ca, cac, fuc

Details for d1w2kh1

PDB Entry: 1w2k, 3 Å

PDB Description: tf7a_4380 complex

PDB Compounds: (H:) blood coagulation factor viia

SCOPe Domain Sequences for d1w2kh1:

Sequence, based on SEQRES records:

>d1w2kh1 b.47.1.2 (H:16-257) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Sequence, based on observed residues (ATOM records):

>d1w2kh1 b.47.1.2 (H:16-257) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkspniteymfcagysdg
skdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrsep
rpgvllrapfp

Timeline for d1w2kh1:

• d1w2kh1 first appeared in SCOP 1.73
  
• d1w2kh1 appears in SCOPe 2.01
  
• d1w2kh1 appears in SCOPe 2.03
  
• d1w2kh1 appears in the current release, SCOPe 2.08, called d1w2kh_