SCOPe 2.08: Domain d1w2ha_: 1w2h A:

Lineage for d1w2ha_ (1w2h A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein automated matches [190087] (15 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:1773] [186809] (11 PDB entries)

8. Domain d1w2ha_: 1w2h A: [120582]
   automated match to d1g3ua_
   complexed with act, atm

Details for d1w2ha_

PDB Entry: 1w2h, 2 Å

PDB Description: crystal structure of mycobacterium tuberculosis thymidylate kinase complexed with azidothymidine monophosphate (azt-mp) (2.0 a resolution)

PDB Compounds: (A:) thymidylate kinase tmk

SCOPe Domain Sequences for d1w2ha_:

Sequence, based on SEQRES records:

>d1w2ha_ c.37.1.1 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgraqrdpgrardnyerdaelqqrtgavya
elaaqgwggrwlvvgadvdpgrlaatlap

Sequence, based on observed residues (ATOM records):

>d1w2ha_ c.37.1.1 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagerdaelqqrtgavyaelaaqgwggrwlvvgadv
dpgrlaatlap

Timeline for d1w2ha_:

• d1w2ha_ first appeared in SCOP 1.73, called d1w2ha1
  
• d1w2ha_ appears in SCOPe 2.07