SCOPe 2.06: Domain d1vyqb_: 1vyq B:

Lineage for d1vyqb_ (1vyq B:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.85: beta-clip [51268] (7 superfamilies)
   double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll

4. Superfamily b.85.4: dUTPase-like [51283] (2 families)
   forms tight trimer through an additional beta-sheet in each subunit
   subunit beta-sheets are orthogonally packed around the three-fold axis

5. Family b.85.4.1: dUTPase-like [51284] (5 proteins)

6. Protein automated matches [190798] (8 species)
   not a true protein

7. Species Plasmodium falciparum [TaxId:36329] [188061] (4 PDB entries)

8. Domain d1vyqb_: 1vyq B: [120549]
   Other proteins in same PDB: d1vyqa1
   automated match to d1vyqa1
   complexed with dux

Details for d1vyqb_

PDB Entry: 1vyq, 2.4 Å

PDB Description: novel inhibitors of plasmodium falciparum dutpase provide a platform for anti-malarial drug design

PDB Compounds: (B:) deoxyuridine 5'-triphosphate nucleotidohydrolase

SCOPe Domain Sequences for d1vyqb_:

Sequence, based on SEQRES records:

>d1vyqb_ b.85.4.1 (B:) automated matches {Plasmodium falciparum [TaxId: 36329]}
mhlkivclsdevremyknhkthhegdsgldlfivkdevlkpksttfvklgikaialqyks
nyyykceksenkkkdddksnivntsfllfprssisktplrlansiglidagyrgeiiaal
dntsdqeyhikkndklvqlvsftgeplsfelvee

Sequence, based on observed residues (ATOM records):

>d1vyqb_ b.85.4.1 (B:) automated matches {Plasmodium falciparum [TaxId: 36329]}
mhlkivclsdevremyknhkthhegdsgldlfivkdevlkpksttfvklgikaialqyks
nyyyknivntsfllfprssisktplrlansiglidagyrgeiiaaldntsdqeyhikknd
klvqlvsftgeplsfelvee

Timeline for d1vyqb_:

• d1vyqb_ first appeared in SCOP 1.73, called d1vyqb1
  
• d1vyqb_ appears in SCOPe 2.05
  
• d1vyqb_ appears in SCOPe 2.07
  
• d1vyqb_ appears in the current release, SCOPe 2.08