SCOP 1.73: Domain d1vrwb1: 1vrw B:97-425

Lineage for d1vrwb1 (1vrw B:97-425)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Enoyl-ACP reductase [51791] (6 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [82296] (11 PDB entries)

8. Domain d1vrwb1: 1vrw B:97-425 [120485]
   automatically matched to 1VRW A:97-425
   complexed with nad

Details for d1vrwb1

PDB Entry: 1vrw, 2.4 Å

PDB Description: crystal structure analysis of plasmodium falciparum enoyl-acyl- carrier-protein reductase with nadh

PDB Compounds: (B:) enoyl-acyl carrier reductase

SCOP Domain Sequences for d1vrwb1:

Sequence, based on SEQRES records:

>d1vrwb1 c.2.1.2 (B:97-425) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntnq
nknrnshdvhnimnnsgekeekknsasqnytfidyaieysekyaplrqkllstdigsvas
fllsresraitgqtiyvdnglnimflpdd

Sequence, based on observed residues (ATOM records):

>d1vrwb1 c.2.1.2 (B:97-425) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainkytfidyaieys
ekyaplrqkllstdigsvasfllsresraitgqtiyvdnglnimflpdd

Timeline for d1vrwb1:

• d1vrwb1 is new in SCOP 1.73
  
• d1vrwb1 appears in SCOP 1.75
  
• d1vrwb1 appears in the current release, SCOPe 2.08, called d1vrwb_