SCOPe 2.08: Domain d1ve2a1: 1ve2 A:1-235

Lineage for d1ve2a1 (1ve2 A:1-235)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.90: Tetrapyrrole methylase [53789] (1 superfamily)
   consists of two non-similar domains
   Domain 1 has parallel sheet of 5 strands, order 32415
   Domain 2 has mixed sheet of 5 strands, order 12534; strands 4 & 5 are antiparallel to the rest

4. Superfamily c.90.1: Tetrapyrrole methylase [53790] (2 families)

5. Family c.90.1.1: Tetrapyrrole methylase [53791] (8 proteins)
   Pfam PF00590

6. Protein Uroporphyrin-III C-methyltransferase (SUMT, UROM, CobA) [117736] (2 species)

7. Species Thermus thermophilus [TaxId:274] [142780] (1 PDB entry)
   Uniprot Q53WA2 1-235

8. Domain d1ve2a1: 1ve2 A:1-235 [120008]
   Other proteins in same PDB: d1ve2b_

Details for d1ve2a1

PDB Entry: 1ve2, 1.8 Å

PDB Description: Crystal structure of uroporphyrin-III-C-methyltransferase from thermus thermophilus

PDB Compounds: (A:) Uroporphyrin-III C-methyltransferase

SCOPe Domain Sequences for d1ve2a1:

Sequence, based on SEQRES records:

>d1ve2a1 c.90.1.1 (A:1-235) Uroporphyrin-III C-methyltransferase (SUMT, UROM, CobA) {Thermus thermophilus [TaxId: 274]}
mrgkvylvgagfggpehltlkalrvlevaevvlhdrlvhpgvlalakgelvpvgkegygg
ktpqeaitarlialaregrvvarlkggdpmvfgrggeealalrragipfevvpgvtsavg
alsalglplthrglarsfavatghdpalplpradtlvllmplhtlgglkerllerfppet
plallarvgwpgeavrlgrvedlpglgeglpspallvvgkvvglygellpkdhgl

Sequence, based on observed residues (ATOM records):

>d1ve2a1 c.90.1.1 (A:1-235) Uroporphyrin-III C-methyltransferase (SUMT, UROM, CobA) {Thermus thermophilus [TaxId: 274]}
mrgkvylvgagfggpehltlkalrvlevaevvlhdrlvhpgvlalakgelvpvktpqeai
tarlialaregrvvarlkggdpmvfgrggeealalrragipfevvpgvtsavgalsalgl
plthrglarsfavatghdpalplpradtlvllmglkerllerfppetplallarvgwpge
avrlgrvedlpglgeglpspallvvgkvvglygellpkdhgl

Timeline for d1ve2a1:

• d1ve2a1 first appeared in SCOP 1.73
  
• d1ve2a1 appears in SCOPe 2.07