SCOP 1.75: Domain d1v59a2: 1v59 A:161-282

Lineage for d1v59a2 (1v59 A:161-282)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (8 families)

5. Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (15 proteins)
   duplication: both domains have similar folds and functions
   most members of the family contain common C-terminal alpha+beta domain

6. Protein Dihydrolipoamide dehydrogenase [51959] (8 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [63950] (2 PDB entries)

8. Domain d1v59a2: 1v59 A:161-282 [119839]
   Other proteins in same PDB: d1v59a3, d1v59b3
   automatically matched to d1jeha2
   complexed with fad, nad, po4

Details for d1v59a2

PDB Entry: 1v59, 2.2 Å

PDB Description: Crystal structure of yeast lipoamide dehydrogenase complexed with NAD+

PDB Compounds: (A:) dihydrolipoamide dehydrogenase

SCOP Domain Sequences for d1v59a2:

Sequence; same for both SEQRES and ATOM records:

>d1v59a2 c.3.1.5 (A:161-282) Dihydrolipoamide dehydrogenase {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
pgieideekivsstgalslkeipkrltiigggiiglemgsvysrlgskvtvvefqpqiga
smdgevakatqkflkkqgldfklstkvisakrnddknvveivvedtktnkqenleaevll
va

Timeline for d1v59a2:

• d1v59a2 first appeared in SCOP 1.73
  
• d1v59a2 appears in SCOPe 2.01
  
• d1v59a2 appears in the current release, SCOPe 2.08