SCOPe 2.08: Domain d1uzla1: 1uzl A:9-247

Lineage for d1uzla1 (1uzl A:9-247)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein beta-keto acyl carrier protein reductase [51788] (8 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [141875] (2 PDB entries)
   Uniprot P0A5Y4 9-245! Uniprot P0A5Y4 9-247

8. Domain d1uzla1: 1uzl A:9-247 [119809]
   Other proteins in same PDB: d1uzlb_
   complexed with cs

Details for d1uzla1

PDB Entry: 1uzl, 2 Å

PDB Description: maba from mycobacterium tuberculosis

PDB Compounds: (A:) 3-oxoacyl-[acyl-carrier protein] reductase

SCOPe Domain Sequences for d1uzla1:

Sequence, based on SEQRES records:

>d1uzla1 c.2.1.2 (A:9-247) beta-keto acyl carrier protein reductase {Mycobacterium tuberculosis [TaxId: 1773]}
akppfvsrsvlvtggnrgiglaiaqrlaadghkvavthrgsgapkglfgvecdvtdsdav
draftaveehqgpvevlvsnaglsadaflmrmteekfekvinanltgafrvaqrasrsmq
rnkfgrmifigsvsgswgignqanyaaskagvigmarsiarelskanvtanvvapgyidt
dmtralderiqqgalqfipakrvgtpaevagvvsflasedasyisgavipvdggmgmgh

Sequence, based on observed residues (ATOM records):

>d1uzla1 c.2.1.2 (A:9-247) beta-keto acyl carrier protein reductase {Mycobacterium tuberculosis [TaxId: 1773]}
akppfvsrsvlvtggnrgiglaiaqrlaadghkvavthrgsgapkglfgvecdvtdsdav
draftaveehqgpvevlvsnaglsadmteekfekvinanltgafrvaqrasrsmqrnkfg
rmifigsvsgswgqanyaaskagvigmarsiarelskanvtanvvapgyidtdmtralde
riqqgalqfipakrvgtpaevagvvsflasedasyisgavipvdggmgmgh

Timeline for d1uzla1:

• d1uzla1 first appeared in SCOP 1.73
  
• d1uzla1 appears in SCOPe 2.07