SCOP 1.75: Domain d1u6al2: 1u6a L:108-213

Lineage for d1u6al2 (1u6a L:108-213)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (132 PDB entries)
   SQ NA # humanized antibody
   Uniprot P01834 # KAC_HUMAN Ig kappa chain C region
   SQ P01834 # KAC_HUMAN Ig kappa chain C region.
   SQ NA # engineered antibody
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d1u6al2: 1u6a L:108-213 [119567]
   Other proteins in same PDB: d1u6ah1, d1u6ah2, d1u6al1
   automatically matched to d1rhha2

Details for d1u6al2

PDB Entry: 1u6a, 2.81 Å

PDB Description: Crystal Structure of the Broadly Neutralizing Anti-HIV Fab F105

PDB Compounds: (L:) f105 light chain

SCOP Domain Sequences for d1u6al2:

Sequence; same for both SEQRES and ATOM records:

>d1u6al2 b.1.1.2 (L:108-213) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrge

Timeline for d1u6al2:

• d1u6al2 first appeared in SCOP 1.73
  
• d1u6al2 appears in SCOPe 2.01
  
• d1u6al2 appears in the current release, SCOPe 2.08