Lineage for d1tzgh2 (1tzg H:114-232)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 651987Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 651988Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 654118Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
  6. 655111Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)
  7. 655115Species Human (Homo sapiens) [TaxId:9606] [88575] (150 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
  8. 655171Domain d1tzgh2: 1tzg H:114-232 [119397]
    Other proteins in same PDB: d1tzgh1, d1tzgi1, d1tzgl1, d1tzgl2, d1tzgm1, d1tzgm2
    automatically matched to d1ngzb2
    complexed with gol

Details for d1tzgh2

PDB Entry: 1tzg (more details), 2.2 Å

PDB Description: Crystal structure of HIV-1 neutralizing human Fab 4E10 in complex with a 13-residue peptide containing the 4E10 epitope on gp41
PDB Compounds: (H:) Fab 4E10

SCOP Domain Sequences for d1tzgh2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1tzgh2 b.1.1.2 (H:114-232) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdk

SCOP Domain Coordinates for d1tzgh2:

Click to download the PDB-style file with coordinates for d1tzgh2.
(The format of our PDB-style files is described here.)

Timeline for d1tzgh2: