Lineage for d1t7ia1 (1t7i A:1-99)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 803906Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 803907Superfamily b.50.1: Acid proteases [50630] (3 families) (S)
  5. 803908Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 804470Protein Simian immunodeficiency virus (SIV) protease [50636] (1 species)
  7. 804471Species Simian immunodeficiency virus, different strains [TaxId:11723] [50637] (16 PDB entries)
  8. 804472Domain d1t7ia1: 1t7i A:1-99 [119166]
    automatically matched to d1k6ca_
    complexed with 017, act, po4; mutant

Details for d1t7ia1

PDB Entry: 1t7i (more details), 1.35 Å

PDB Description: the structural and thermodynamic basis for the binding of tmc114, a next-generation hiv-1 protease inhibitor.
PDB Compounds: (A:) Pol polyprotein

SCOP Domain Sequences for d1t7ia1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1t7ia1 b.50.1.1 (A:1-99) Simian immunodeficiency virus (SIV) protease {Simian immunodeficiency virus, different strains [TaxId: 11723]}

SCOP Domain Coordinates for d1t7ia1:

Click to download the PDB-style file with coordinates for d1t7ia1.
(The format of our PDB-style files is described here.)

Timeline for d1t7ia1: