SCOPe 2.06: Domain d1t1fc_: 1t1f C:

Lineage for d1t1fc_ (1t1f C:)

1. Root: SCOPe 2.06

2. Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (2 families)

5. Family e.1.1.1: Serpins [56575] (17 proteins)
   automatically mapped to Pfam PF00079

6. Protein Antithrombin [56584] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56586] (27 PDB entries)
   Uniprot P01008

8. Domain d1t1fc_: 1t1f C: [119109]
   automated match to d2anti_
   complexed with gol, iod

Details for d1t1fc_

PDB Entry: 1t1f, 2.75 Å

PDB Description: crystal structure of native antithrombin in its monomeric form

PDB Compounds: (C:) antithrombin-III

SCOPe Domain Sequences for d1t1fc_:

Sequence, based on SEQRES records:

>d1t1fc_ e.1.1.1 (C:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
gspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfatt
fyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihf
ffaklncrlyrkankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeq
sraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfyk
adgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltp
evlqewldeleemmlcvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrdd
lyvsdafhkaflevneegseaaastavviagrslnpnrvcfkanrpflvfirevplntii
fmgrvanpcvk

Sequence, based on observed residues (ATOM records):

>d1t1fc_ e.1.1.1 (C:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
gspvdictakprdipmnpmciyreqkipeatnrrvwelskansrfattfyqhladskndn
dniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrk
ankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnk
tegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmy
qegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldelee
mmlcvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkafl
evneegseaaastavviagrslnpnrvcfkanrpflvfirevplntiifmgrvanpcvk

Timeline for d1t1fc_:

• d1t1fc_ first appeared in SCOP 1.73, called d1t1fc1
  
• d1t1fc_ appears in SCOPe 2.05
  
• d1t1fc_ appears in SCOPe 2.07
  
• d1t1fc_ appears in the current release, SCOPe 2.08