SCOPe 2.07: Domain d1sn6a2: 1sn6 A:1-80

Lineage for d1sn6a2 (1sn6 A:1-80)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.64: Saposin-like [47861] (2 superfamilies)
   5 helices; folded leaf, closed

4. Superfamily a.64.1: Saposin [47862] (5 families)
   Lipid-binding can promote conformational changes and oligomerisation in some members

5. Family a.64.1.1: NKL-like [47863] (4 proteins)

6. Protein Saposin C [89077] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89078] (11 PDB entries)

8. Domain d1sn6a2: 1sn6 A:1-80 [118972]
   Other proteins in same PDB: d1sn6a3
   automated match to d1m12a_

Details for d1sn6a2

PDB Entry: 1sn6

PDB Description: nmr solution structure of human saposin c in sds micelles

PDB Compounds: (A:) Proactivator polypeptide

SCOPe Domain Sequences for d1sn6a2:

Sequence; same for both SEQRES and ATOM records:

>d1sn6a2 a.64.1.1 (A:1-80) Saposin C {Human (Homo sapiens) [TaxId: 9606]}
sdvycevceflvkevtklidnnktekeildafdkmcsklpkslseecqevvdtygssils
illeevspelvcsmlhlcsg

Timeline for d1sn6a2:

• d1sn6a2 first appeared in SCOP 1.73, called d1sn6a1
  
• d1sn6a2 appears in SCOPe 2.06
  
• d1sn6a2 appears in the current release, SCOPe 2.08