SCOPe 2.08: Domain d1smre_: 1smr E:

Lineage for d1smre_ (1smr E:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonym: renin) [50667] (3 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [50670] (1 PDB entry)

8. Domain d1smre_: 1smr E: [118628]
   duplicate of 1SMR A

Details for d1smre_

PDB Entry: 1smr, 2 Å

PDB Description: the 3-d structure of mouse submaxillary renin complexed with a decapeptide inhibitor ch-66 based on the 4-16 fragment of rat angiotensinogen

PDB Compounds: (E:) renin

SCOPe Domain Sequences for d1smre_:

Sequence, based on SEQRES records:

>d1smre_ b.50.1.2 (E:) Chymosin (synonym: renin) {Mouse (Mus musculus) [TaxId: 10090]}
tdlispvvltnylnsqyygeigigtppqtfkvifdtgsanlwvpstkcsrlylacgihsl
yessdsssymengddftihygsgrvkgflsqdsvtvggitvtqtfgevtqlplipfmlaq
fdgvlgmgfpaqavggvtpvfdhilsqgvlkekvfsvyynrgphllggevvlggsdpqhy
qgdfhyvslsktdswqitmkgvsvgsstllceegcevvvdtgssfisaptsslklimqal
gakekrlheyvvscsqvptlpdisfnlggraytlsstdyvlqypnrrdklctvalhamdi
ppptgpvwvlgatfirkfytefdrhnnrigfalar

Sequence, based on observed residues (ATOM records):

>d1smre_ b.50.1.2 (E:) Chymosin (synonym: renin) {Mouse (Mus musculus) [TaxId: 10090]}
tdlispvvltnylnsqyygeigigtppqtfkvifdtgsanlwvpstkcsrlylacgihsl
yessdsssymengddftihygsgrvkgflsqdsvtvggitvtqtfgevtqlplipfmlaq
fdgvlgmgfpaqavggvtpvfdhilsqgvlkekvfsvyynrgphllggevvlggsdpqhy
qgdfhyvslsktdswqitmkgvsvgsstllceegcevvvdtgssfisaptsslklimqal
gakekrlheyvvscsqvptlpdisfnlggraytlsstdyvlqrdklctvalhamdipppt
gpvwvlgatfirkfytefdrhnnrigfalar

Timeline for d1smre_:

• d1smre_ first appeared in SCOP 1.73
  
• d1smre_ appears in SCOPe 2.07