Lineage for Protein: Dual specificity mitogen-activated protein kinase kinase 1, Mek1

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. Protein Dual specificity mitogen-activated protein kinase kinase 1, Mek1 [118137] (2 species)
    OPK group (?); MAPKK subfamily; serine/threonine kinase

Species:

  1. Human (Homo sapiens) [TaxId:9606] [118138] (36 PDB entries)
    Uniprot Q02750 61-381
    1. Domain for 1s9j:
    2. Domain for 2p55:
    3. Domain for 3dv3:
    4. Domain for 3dy7:
    5. Domain for 3e8n:
    6. Domain for 3eqb:
    7. Domain for 3eqc:
    8. Domain for 3eqd:
    9. Domain for 3eqf:
    10. Domain for 3eqg:
    11. Domain for 3eqh:
    12. Domain for 3eqi:
    13. Domain for 3v01:
    14. Domain for 3v04:
    15. Domains for 3vvh:
      1. Domain d3vvha1: 3vvh A:62-382 [218119]
        Other proteins in same PDB: d3vvha2, d3vvhb2, d3vvhc2
        automated match to d1s9ja_
        complexed with 4bm, atp, mg
      2. Domain d3vvhb1: 3vvh B:62-382 [218120]
        Other proteins in same PDB: d3vvha2, d3vvhb2, d3vvhc2
        automated match to d1s9ja_
        complexed with 4bm, atp, mg
      3. Domain d3vvhc1: 3vvh C:62-381 [218121]
        Other proteins in same PDB: d3vvha2, d3vvhb2, d3vvhc2
        automated match to d1s9ja_
        complexed with 4bm, atp, mg
    16. Domain for 4lmn:
    17. Domains for 4mne:
      1. Domain d4mnea_: 4mne A: [257091]
        Other proteins in same PDB: d4mneb_, d4mnec_, d4mnef_, d4mneg_
        automated match to d1s9ja_
        complexed with 573, acp, cl, mg
      2. Domain d4mned_: 4mne D: [257092]
        Other proteins in same PDB: d4mneb_, d4mnec_, d4mnef_, d4mneg_
        automated match to d1s9ja_
        complexed with 573, acp, cl, mg
      3. Domain d4mnee_: 4mne E: [257093]
        Other proteins in same PDB: d4mneb_, d4mnec_, d4mnef_, d4mneg_
        automated match to d1s9ja_
        complexed with 573, acp, cl, mg
      4. Domain d4mneh_: 4mne H: [257094]
        Other proteins in same PDB: d4mneb_, d4mnec_, d4mnef_, d4mneg_
        automated match to d1s9ja_
        complexed with 573, acp, cl, mg
    18. Domain for 4u7z:
    19. Domain for 4u80:
    20. Domain for 4u81:
    21. Domain for 5bx0:
    22. Domains for 5eym:
      1. Domain d5eyma_: 5eym A: [321296]
        automated match to d1s9ia_
        complexed with 5u5, ca
      2. Domain d5eymb_: 5eym B: [321678]
        automated match to d1s9ia_
        complexed with 5u5, ca
    23. Domain for 5hze:
    24. Domain for 6pp9:
    25. Domain for 6u2g:
    26. Domain for 6v2w:
    27. Domain for 7b3m:
    28. Domain for 7b7r:
    29. Domain for 7b94:
    30. Domain for 7b9l:
    31. Domain for 7m0t:
    32. Domain for 7m0u:
    33. Domain for 7m0v:
    34. Domain for 7m0w:
    35. Domain for 7m0x:
    36. Domain for 7m0z:
  2. Rabbit (Oryctolagus cuniculus) [TaxId:9986] [390304] (6 PDB entries)
    1. Domain for 7jur:
    2. Domain for 7jus:
    3. Domain for 7jut:
    4. Domain for 7juu:
    5. Domain for 7juw:
    6. Domain for 7juy:

More info for Protein Dual specificity mitogen-activated protein kinase kinase 1, Mek1 from d.144.1.7: Protein kinases, catalytic subunit

Timeline for Protein Dual specificity mitogen-activated protein kinase kinase 1, Mek1 from d.144.1.7: Protein kinases, catalytic subunit:

  • Protein Dual specificity mitogen-activated protein kinase kinase 1, Mek1 from d.144.1.7: Protein kinases, catalytic subunit first appeared in SCOP 1.71
  • Protein Dual specificity mitogen-activated protein kinase kinase 1, Mek1 from d.144.1.7: Protein kinases, catalytic subunit appears in SCOPe 2.07