Lineage for Species: Leishmania mexicana mexicana [TaxId: 44270]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108389Family c.36.1.6: TK-like Pyr module [88735] (2 protein domains)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 2108404Protein Transketolase (TK), Pyr module [88736] (4 species)
  7. 2108423Species Leishmania mexicana mexicana [TaxId:44270] [117521] (1 PDB entry)
    Uniprot Q8MPM3

PDB entry in Species: Leishmania mexicana mexicana [TaxId: 44270]:

More info for Species Leishmania mexicana mexicana [TaxId:44270] from c.36.1.6 Transketolase (TK), Pyr module

Timeline for Species Leishmania mexicana mexicana [TaxId:44270] from c.36.1.6 Transketolase (TK), Pyr module: