Lineage for Species: Guinea pig (Cavia porcellus) [TaxId: 10141]

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 975118Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 975119Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 975436Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 975463Protein 11-beta-hydroxysteroid dehydrogenase 1 [117423] (3 species)
  7. 975464Species Guinea pig (Cavia porcellus) [TaxId:10141] [117425] (4 PDB entries)
    Uniprot Q6QLL4 23-296

PDB entries in Species: Guinea pig (Cavia porcellus) [TaxId: 10141]:

  1. Domain(s) for 1xse:
    1. 975473Domain d1xsea_: 1xse A: [115925]
      complexed with ndp
    2. 975474Domain d1xseb_: 1xse B: [115926]
      complexed with ndp
  2. Domain(s) for 3dwf:
    1. 975469Domain d3dwfa1: 3dwf A:25-293 [174301]
      automated match to d1xsea_
      complexed with gol, nap, so4; mutant
    2. 975470Domain d3dwfb_: 3dwf B: [174302]
      automated match to d1xsea_
      complexed with gol, nap, so4; mutant
    3. 975471Domain d3dwfc1: 3dwf C:24-295 [174303]
      automated match to d1xsea_
      complexed with gol, nap, so4; mutant
    4. 975472Domain d3dwfd_: 3dwf D: [174304]
      automated match to d1xsea_
      complexed with gol, nap, so4; mutant
  3. Domain(s) for 3g49:
    1. 975475Domain d3g49a_: 3g49 A: [176338]
      automated match to d1xsea_
      complexed with 3g4, nap
    2. 975476Domain d3g49b_: 3g49 B: [176339]
      automated match to d1xsea_
      complexed with 3g4, nap
    3. 975477Domain d3g49c_: 3g49 C: [176340]
      automated match to d1xsea_
      complexed with 3g4, nap
    4. 975478Domain d3g49d_: 3g49 D: [176341]
      automated match to d1xsea_
      complexed with 3g4, nap
  4. Domain(s) for 3lz6:
    1. 975465Domain d3lz6a_: 3lz6 A: [180653]
      automated match to d1xsea_
      complexed with a0d, nap
    2. 975466Domain d3lz6b_: 3lz6 B: [180654]
      automated match to d1xsea_
      complexed with a0d, nap
    3. 975467Domain d3lz6c_: 3lz6 C: [180655]
      automated match to d1xsea_
      complexed with a0d, nap
    4. 975468Domain d3lz6d_: 3lz6 D: [180656]
      automated match to d1xsea_
      complexed with a0d, nap

More info for Species Guinea pig (Cavia porcellus) [TaxId:10141] from c.2.1.2 11-beta-hydroxysteroid dehydrogenase 1

Timeline for Species Guinea pig (Cavia porcellus) [TaxId:10141] from c.2.1.2 11-beta-hydroxysteroid dehydrogenase 1: