Lineage for Species: Human (Homo sapiens)

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 574151Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 574152Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 574451Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (53 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 574473Protein 11-beta-hydroxysteroid dehydrogenase 1 [117423] (2 species)
  7. 574477Species Human (Homo sapiens) [TaxId:9606] [117424] (3 PDB entries)

PDB entries in Species: Human (Homo sapiens):

  1. Domain(s) for 1xu7:
    1. 574482Domain d1xu7a_: 1xu7 A: [116048]
    2. 574483Domain d1xu7b_: 1xu7 B: [116049]
    3. 574484Domain d1xu7c_: 1xu7 C: [116050]
    4. 574485Domain d1xu7d_: 1xu7 D: [116051]
      complexed with cps, ndp; mutant
  2. Domain(s) for 1xu9:
    1. 574478Domain d1xu9a_: 1xu9 A: [116052]
    2. 574479Domain d1xu9b_: 1xu9 B: [116053]
    3. 574480Domain d1xu9c_: 1xu9 C: [116054]
    4. 574481Domain d1xu9d_: 1xu9 D: [116055]
      complexed with cps, mes, ndp; mutant
  3. Domain(s) for 2bel:
    1. 574486Domain d2bela_: 2bel A: [116694]
    2. 574487Domain d2belb_: 2bel B: [116695]
    3. 574488Domain d2belc_: 2bel C: [116696]
    4. 574489Domain d2beld_: 2bel D: [116697]
      complexed with cbo, cl, nap

More info for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.2 11-beta-hydroxysteroid dehydrogenase 1

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.2 11-beta-hydroxysteroid dehydrogenase 1: