Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 has additional subdomain(s) that are not in the common domain |
Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) [117421] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [117422] (3 PDB entries) Uniprot Q16698 35-328 |
Domain d1w6ua_: 1w6u A: [114288] complexed with hxc, nap |
Domain d1w6ub_: 1w6u B: [114289] complexed with hxc, nap |
Domain d1w6uc_: 1w6u C: [114290] complexed with hxc, nap |
Domain d1w6ud_: 1w6u D: [114291] complexed with hxc, nap |
Domain d1w73a_: 1w73 A: [114307] complexed with gol, nap |
Domain d1w73b_: 1w73 B: [114308] complexed with gol, nap |
Domain d1w73c_: 1w73 C: [114309] complexed with gol, nap |
Domain d1w73d_: 1w73 D: [114310] complexed with gol, nap |
Domain d1w8da_: 1w8d A: [114364] complexed with gol, nap |
Domain d1w8db_: 1w8d B: [114365] complexed with gol, nap |
Domain d1w8dc_: 1w8d C: [114366] complexed with gol, nap |
Domain d1w8dd_: 1w8d D: [114367] complexed with gol, nap |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.2 2,4-dienoyl-CoA reductase, mitochondrial (DECR):