SCOPe 2.07: Protein: 2,4-dienoyl-CoA reductase, mitochondrial (DECR)

Lineage for Protein: 2,4-dienoyl-CoA reductase, mitochondrial (DECR)

Root: SCOPe 2.07
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) [117421] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [117422] (3 PDB entries)
Uniprot Q16698 35-328
1. Domains for 1w6u:
  1. Domain d1w6ua_: 1w6u A: [114288]
    complexed with hxc, nap
  2. Domain d1w6ub_: 1w6u B: [114289]
    complexed with hxc, nap
  3. Domain d1w6uc_: 1w6u C: [114290]
    complexed with hxc, nap
  4. Domain d1w6ud_: 1w6u D: [114291]
    complexed with hxc, nap
2. Domains for 1w73:
  1. Domain d1w73a_: 1w73 A: [114307]
    complexed with gol, nap
  2. Domain d1w73b_: 1w73 B: [114308]
    complexed with gol, nap
  3. Domain d1w73c_: 1w73 C: [114309]
    complexed with gol, nap
  4. Domain d1w73d_: 1w73 D: [114310]
    complexed with gol, nap
3. Domains for 1w8d:
  1. Domain d1w8da_: 1w8d A: [114364]
    complexed with gol, nap
  2. Domain d1w8db_: 1w8d B: [114365]
    complexed with gol, nap
  3. Domain d1w8dc_: 1w8d C: [114366]
    complexed with gol, nap
  4. Domain d1w8dd_: 1w8d D: [114367]
    complexed with gol, nap

More info for Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) from c.2.1.2: Tyrosine-dependent oxidoreductases:

Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) from c.2.1.2: Tyrosine-dependent oxidoreductases first appeared in SCOP 1.71
Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOPe 2.06
Protein 2,4-dienoyl-CoA reductase, mitochondrial (DECR) from c.2.1.2: Tyrosine-dependent oxidoreductases appears in the current release, SCOPe 2.08