Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2725421Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 2725422Superfamily a.118.1: ARM repeat [48371] (28 families) (S)
  5. 2725961Family a.118.1.19: Exportin HEAT-like repeat [117002] (2 proteins)
    Pfam PF08389, Pfam PF08767; full length proteins have several extra helices at C-terminus
    this is a repeat family; one repeat unit is 3gb8 A:533-577 found in domain
  6. 2725962Protein Exportin-1 (Xpo1, Crm1) [117003] (1 species)
  7. 2725963Species Human (Homo sapiens) [TaxId:9606] [117004] (2 PDB entries)
    Uniprot O14980 707-1027

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1w9c:
    1. 2725964Domain d1w9ca_: 1w9c A: [114410]
      proteolytic fragment spanning six C-terminal HEAT repeats
    2. 2725965Domain d1w9cb_: 1w9c B: [114411]
      proteolytic fragment spanning six C-terminal HEAT repeats
  2. Domain(s) for 3gb8:
    • 2725966Domain d3gb8a_: 3gb8 A: [246276]
      Other proteins in same PDB: d3gb8b1, d3gb8b2, d3gb8b3
      protein/RNA complex
      applies to all domains of a family if the common domain is composed of a different number of small repeating units

More info for Species Human (Homo sapiens) [TaxId:9606] from a.118.1.19 Exportin-1 (Xpo1, Crm1)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.118.1.19 Exportin-1 (Xpo1, Crm1):