Lineage for d2belb_ (2bel B:)

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 574151Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 574152Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 574451Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (53 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 574473Protein 11-beta-hydroxysteroid dehydrogenase 1 [117423] (2 species)
  7. 574477Species Human (Homo sapiens) [TaxId:9606] [117424] (3 PDB entries)
  8. 574487Domain d2belb_: 2bel B: [116695]

Details for d2belb_

PDB Entry: 2bel (more details), 2.11 Å

PDB Description: structure of human 11-beta-hydroxysteroid dehydrogenase in complex with nadp and carbenoxolone

SCOP Domain Sequences for d2belb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2belb_ c.2.1.2 (B:) 11-beta-hydroxysteroid dehydrogenase 1 {Human (Homo sapiens)}

SCOP Domain Coordinates for d2belb_:

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(The format of our PDB-style files is described here.)

Timeline for d2belb_: