SCOPe 2.05: Domain d1yg2a_: 1yg2 A:

Lineage for d1yg2a_ (1yg2 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (85 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.61: PadR-like [116807] (3 proteins)
   Pfam PF03551; related to the MarR-like family (Pfam PF01047)

6. Protein Hypothetical protein AphA [116810] (1 species)
   contains extra C-terminal dimerisation domain

7. Species Vibrio cholerae [TaxId:666] [116811] (1 PDB entry)
   Uniprot Q9X399 # "winged helix" domain: 1-87, dimerisation domain: 91-179

8. Domain d1yg2a_: 1yg2 A: [116681]
   Structural genomics target

Details for d1yg2a_

PDB Entry: 1yg2, 2.2 Å

PDB Description: structure of the vibrio cholerae virulence activator apha

PDB Compounds: (A:) gene activator AphA

SCOPe Domain Sequences for d1yg2a_:

Sequence, based on SEQRES records:

>d1yg2a_ a.4.5.61 (A:) Hypothetical protein AphA {Vibrio cholerae [TaxId: 666]}
slphviltvlstrdatgyditkefsasigyfwkashqqvyrelnkmgeqglvtcvlepqe
gkpdrkvysitqagrsalgewfdqptahptvrdefsaklmacsvqsaepyrlqlaelvee
srklvahyqeieaayyanpavldkqqrlerltlrrnllvrqawiqwadevlaelnama

Sequence, based on observed residues (ATOM records):

>d1yg2a_ a.4.5.61 (A:) Hypothetical protein AphA {Vibrio cholerae [TaxId: 666]}
slphviltvlstrdatgyditkefsasigyfwkashqqvyrelnkmgeqglvtcvlevys
itqagrsalgewfdqptahptvrdefsaklmacsvqsaepyrlqlaelveesrklvahyq
eieaayyanpavldkqqrlerltlrrnllvrqawiqwadevlaelnama

Timeline for d1yg2a_:

• d1yg2a_ first appeared in SCOP 1.71
  
• d1yg2a_ appears in SCOPe 2.04
  
• d1yg2a_ appears in SCOPe 2.06
  
• d1yg2a_ appears in the current release, SCOPe 2.08