SCOPe 2.08: Domain d1xzxx1: 1xzx X:202-460

Lineage for d1xzxx1 (1xzx X:202-460)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Thyroid hormone receptor beta (TR-beta) [48530] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48531] (22 PDB entries)
   Uniprot P10828 202-460

8. Domain d1xzxx1: 1xzx X:202-460 [116274]
   Other proteins in same PDB: d1xzxx2
   complexed with cac, t3

Details for d1xzxx1

PDB Entry: 1xzx, 2.5 Å

PDB Description: thyroxine-thyroid hormone receptor interactions

PDB Compounds: (X:) Thyroid hormone receptor Beta-1

SCOPe Domain Sequences for d1xzxx1:

Sequence, based on SEQRES records:

>d1xzxx1 a.123.1.1 (X:202-460) Thyroid hormone receptor beta (TR-beta) {Human (Homo sapiens) [TaxId: 9606]}
eelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpedigqapivnapeg
gkvdleafshftkiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslraavry
dpesetltlngemavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllmss
drpglacveriekyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrflh
mkvecptelfpplflevfe

Sequence, based on observed residues (ATOM records):

>d1xzxx1 a.123.1.1 (X:202-460) Thyroid hormone receptor beta (TR-beta) {Human (Homo sapiens) [TaxId: 9606]}
eelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpedigvdleafshft
kiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslraavrydpesetltlnge
mavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllmssdrpglacverie
kyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrflhmkvecptelfpp
lflevfe

Timeline for d1xzxx1:

• d1xzxx1 first appeared in SCOP 1.71, called d1xzxx_
  
• d1xzxx1 appears in SCOPe 2.07