Lineage for d1xu9a_ (1xu9 A:)

  1. Root: SCOPe 2.02
  2. 1143363Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1150729Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 1150730Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 1151047Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 1151074Protein 11-beta-hydroxysteroid dehydrogenase 1 [117423] (3 species)
  7. 1151090Species Human (Homo sapiens) [TaxId:9606] [117424] (20 PDB entries)
    Uniprot P28845
  8. 1151091Domain d1xu9a_: 1xu9 A: [116052]
    complexed with cps, mes, ndp

Details for d1xu9a_

PDB Entry: 1xu9 (more details), 1.55 Å

PDB Description: Crystal Structure of the Interface Closed Conformation of 11b-hydroxysteroid dehydrogenase isozyme 1
PDB Compounds: (A:) Corticosteroid 11-beta-dehydrogenase, isozyme 1

SCOPe Domain Sequences for d1xu9a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1xu9a_ c.2.1.2 (A:) 11-beta-hydroxysteroid dehydrogenase 1 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1xu9a_:

Click to download the PDB-style file with coordinates for d1xu9a_.
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Timeline for d1xu9a_: