SCOP 1.73: Domain d1xsea_: 1xse A:

Lineage for d1xsea_ (1xse A:)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein 11-beta-hydroxysteroid dehydrogenase 1 [117423] (3 species)

7. Species Guinea pig (Cavia porcellus) [TaxId:10141] [117425] (1 PDB entry)

8. Domain d1xsea_: 1xse A: [115925]

Details for d1xsea_

PDB Entry: 1xse, 2.5 Å

PDB Description: crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1

PDB Compounds: (A:) 11beta-hydroxysteroid dehydrogenase type 1

SCOP Domain Sequences for d1xsea_:

Sequence; same for both SEQRES and ATOM records:

>d1xsea_ c.2.1.2 (A:) 11-beta-hydroxysteroid dehydrogenase 1 {Guinea pig (Cavia porcellus) [TaxId: 10141]}
nekfrpemlqgkkvivtgaskgigreiayhlakmgahvvvtarskealqkvvarclelga
asahyiagsmedmtfaeefvaeagnlmggldmlilnhvlynrltffhgeidnvrksmevn
fhsfvvlsvaampmlmqsqgsiavvssvagkitypliapysaskfaldgffstlrseflv
nkvnvsitlcilglidtetaikatsgiylgpaspkeecaleiikgtalrqdemyyvgsrw
vpyllgnpgrkimeflsaaeynwdnvlsneklyg

Timeline for d1xsea_:

• d1xsea_ first appeared in SCOP 1.71
  
• d1xsea_ appears in SCOP 1.75
  
• d1xsea_ appears in the current release, SCOPe 2.08