Lineage for d1xsaa1 (1xsa A:6-152)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.113: Nudix [55810] (1 superfamily)
    beta(2)-alpha-beta(3)-alpha; 3 layers: alpha/beta/alpha; mixed sheet
    contains beta-grasp motif
  4. Superfamily d.113.1: Nudix [55811] (8 families) (S)
  5. Family d.113.1.1: MutT-like [55812] (17 proteins)
  6. Protein Diadenosine tetraphosphate hydrolase (Ap4A hydrolase) [64367] (3 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [118084] (3 PDB entries)
    Uniprot P50583
  8. Domain d1xsaa1: 1xsa A:6-152 [115922]
    Other proteins in same PDB: d1xsaa2, d1xsaa3
    mutant

Details for d1xsaa1

PDB Entry: 1xsa (more details)

PDB Description: Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant)
PDB Compounds: (A:) Bis(5'-nucleosyl)-tetraphosphatase

SCOPe Domain Sequences for d1xsaa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1xsaa1 d.113.1.1 (A:6-152) Diadenosine tetraphosphate hydrolase (Ap4A hydrolase) {Human (Homo sapiens) [TaxId: 9606]}
malracgliifrrclipkvdnnaieflllqasdgihhwtppkghvepgeddletalratq
eeagieagqltiiegfkrelnyvarnkpktviywlaevkdydveirlshehqayrwlgle
eacqlaqfkemkaalqeghqflcsiea

SCOPe Domain Coordinates for d1xsaa1 are not available.

Timeline for d1xsaa1:

View in 3D
Domains from same chain:
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d1xsaa2, d1xsaa3