Lineage for d1xplb2 (1xpl B:168-388)

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2164457Fold c.95: Thiolase-like [53900] (1 superfamily)
    consists of two similar domains related by pseudo dyad; duplication
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32451; strand 5 is antiparallel to the rest
  4. 2164458Superfamily c.95.1: Thiolase-like [53901] (3 families) (S)
  5. 2164936Family c.95.1.2: Chalcone synthase-like [53914] (9 proteins)
  6. 2164937Protein 3-hydroxy-3-methylglutaryl CoA synthase MvaS [110760] (2 species)
    most similar to FabH
  7. 2164963Species Staphylococcus aureus [TaxId:1280] [110761] (5 PDB entries)
    Uniprot Q7A3F6
  8. 2164977Domain d1xplb2: 1xpl B:168-388 [115754]
    Other proteins in same PDB: d1xpla3, d1xpla4, d1xplb3, d1xplb4, d1xplc3, d1xplc4, d1xpld3, d1xpld4
    complexed with caa, so4

Details for d1xplb2

PDB Entry: 1xpl (more details), 2 Å

PDB Description: crystal structure of staphylococcus aureus hmg-coa synthase with acetoacetyl-coa and acetylated cysteine
PDB Compounds: (B:) 3-hydroxy-3-methylglutaryl CoA synthase

SCOPe Domain Sequences for d1xplb2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1xplb2 c.95.1.2 (B:168-388) 3-hydroxy-3-methylglutaryl CoA synthase MvaS {Staphylococcus aureus [TaxId: 1280]}
ilalnedavaytedvydfwrptghkyplvdgalskdayirsfqqswneyakrqgksladf
aslcfhvpftkmgkkalesiidnadettqerlrsgyedavdynryvgniytgslylslis
llenrdlqagetiglfsygsgsvgefysatlvegykdhldqaahkallnnrtevsvdaye
tffkrfddvefdeeqdavhedrhifylsniennvreyhrpe

SCOPe Domain Coordinates for d1xplb2:

Click to download the PDB-style file with coordinates for d1xplb2.
(The format of our PDB-style files is described here.)

Timeline for d1xplb2: