SCOPe 2.05: Domain d1xowa_: 1xow A:

Lineage for d1xowa_ (1xow A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Androgen receptor [63621] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63623] (50 PDB entries)
   Uniprot P10275 671-919

8. Domain d1xowa_: 1xow A: [115717]
   complexed with r18

Details for d1xowa_

PDB Entry: 1xow, 1.8 Å

PDB Description: crystal structure of the human androgen receptor ligand binding domain bound with an androgen receptor nh2-terminal peptide, ar20-30, and r1881

PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d1xowa_:

Sequence, based on SEQRES records:

>d1xowa_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpt
scsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgk
vkpiyfhtq

Sequence, based on observed residues (ATOM records):

>d1xowa_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiatscsrrf
yqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyf
htq

Timeline for d1xowa_:

• d1xowa_ first appeared in SCOP 1.71
  
• d1xowa_ appears in SCOPe 2.04
  
• d1xowa_ appears in SCOPe 2.06
  
• d1xowa_ appears in the current release, SCOPe 2.08