SCOPe 2.03: Domain d1xmn.3: 1xmn E:,F:

Lineage for d1xmn.3 (1xmn E:,F:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (168 PDB entries)
   Uniprot P00734 331-361,364-421 ! Uniprot P00734 334-360 364-510 518-619 ! Uniprot P00734 328-620 ! Uniprot P00734 355-621 ! Uniprot P00734 328-620

8. Domain d1xmn.3: 1xmn E:,F: [115497]
   complexed with 0g6, gol, na

Details for d1xmn.3

PDB Entry: 1xmn, 1.85 Å

PDB Description: crystal structure of thrombin bound to heparin

PDB Compounds: (E:) Thrombin light chain, (F:) Thrombin heavy chain

SCOPe Domain Sequences for d1xmn.3:

Sequence, based on SEQRES records:

>g1xmn.3 b.47.1.2 (E:,F:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
eadcglrplfekksledkterellesyidXivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwta
nvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfv
mkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Sequence, based on observed residues (ATOM records):

>g1xmn.3 b.47.1.2 (E:,F:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
eadcglrplfekksledkterellesyidXivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtg
qpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspf
nnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Timeline for d1xmn.3:

• d1xmn.3 first appeared in SCOP 1.71
  
• d1xmn.3 appears in SCOPe 2.02
  
• d1xmn.3 appears in SCOPe 2.04
  
• d1xmn.3 appears in the current release, SCOPe 2.08