SCOP 1.73: Domain d1xkta_: 1xkt A:

Lineage for d1xkta_ (1xkt A:)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (35 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.22: Thioesterase domain of polypeptide, polyketide and fatty acid synthases [69584] (4 proteins)
   Pfam PF00975

6. Protein Fatty acid synthase [117709] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [117710] (1 PDB entry)

8. Domain d1xkta_: 1xkt A: [115423]

Details for d1xkta_

PDB Entry: 1xkt, 2.6 Å

PDB Description: Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain

PDB Compounds: (A:) fatty acid synthase

SCOP Domain Sequences for d1xkta_:

Sequence, based on SEQRES records:

>d1xkta_ c.69.1.22 (A:) Fatty acid synthase {Human (Homo sapiens) [TaxId: 9606]}
vnlrsllvnpegptlmrlnsvqsserplflvhpiegsttvfhslasrlsiptyglqctra
apldsihslaayyidcirqvqpegpyrvagysygacvafemcsqlqaqqspapthnslfl
fdgsptyvlaytqsyrakltpgceaeaeteaicffvqqftdmehnrvleallplkgleer
vaaavdliikshqgldrqelsfaarsfyyklraaeqytpkakyygnvmllraktggayge
dlgadynlsqvcdgkvsvhviegdhrtllegsglesiisiihssla

Sequence, based on observed residues (ATOM records):

>d1xkta_ c.69.1.22 (A:) Fatty acid synthase {Human (Homo sapiens) [TaxId: 9606]}
vnlrsllvnpegptlmrlnsvqsserplflvhpiegsttvfhslasrlsiptyglqctra
apldsihslaayyidcirqvqpegpyrvagysygacvafemcsqlqaqhnslflfdgspt
ypgceaeaeteaicffvqqftdmehnrvleallplkgleervaaavdliikshqgldrqe
lsfaarsfyyklraaeqytpkakyygnvmllraktglgadynlsqvcdgkvsvhviegdh
rtllesglesiisiihssla

Timeline for d1xkta_:

• d1xkta_ first appeared in SCOP 1.71
  
• d1xkta_ appears in SCOP 1.75
  
• d1xkta_ appears in the current release, SCOPe 2.08, called d1xkta1