SCOP 1.71: Domain d1xdua2: 1xdu A:102-357

Lineage for d1xdua2 (1xdu A:102-357)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (41 families)

5. Family c.66.1.12: Plant O-methyltransferase, C-terminal domain [64111] (5 proteins)

6. Protein Aclacinomycin-10-hydroxylase RdmB [102554] (1 species)
   evolved a different function; binds SAM and SAH

7. Species Streptomyces purpurascens [TaxId:1924] [102555] (4 PDB entries)

8. Domain d1xdua2: 1xdu A:102-357 [115179]
   Other proteins in same PDB: d1xdua1
   complexed with act, sfg

Details for d1xdua2

PDB Entry: 1xdu, 2.7 Å

PDB Description: Crystal structure of Aclacinomycin-10-hydroxylase (RdmB) in complex with Sinefungin (SFG)

SCOP Domain Sequences for d1xdua2:

Sequence, based on SEQRES records:

>d1xdua2 c.66.1.12 (A:102-357) Aclacinomycin-10-hydroxylase RdmB {Streptomyces purpurascens}
hpaqqrawldlngavshadlaftglldvvrtgrpayagrygrpfwedlsadvaladsfda
lmscdedlayeapadaydwsavrhvldvgggnggmlaaialraphlrgtlvelagpaera
rrrfadagladrvtvaegdffkplpvtadvvllsfvllnwsdedaltilrgcvralepgg
rllvldradvegdgadrffstlldlrmltfmggrvrtrdevvdlagsaglalasertsgs
ttlpfdfsileftavs

Sequence, based on observed residues (ATOM records):

>d1xdua2 c.66.1.12 (A:102-357) Aclacinomycin-10-hydroxylase RdmB {Streptomyces purpurascens}
hpaqqrawldlngavshadlaftglldvvrtgrpayagrygrpfwedlsadvaladsfda
lmscdedlayeapadaydwsavrhvldvgggnggmlaaialraphlrgtlvelagpaera
rrrfadagladrvtvaegdffkplpvtadvvllsfvllnwsdedaltilrgcvralepgg
rllvldradrffstlldlrmltfmggrvrtrdevvdlagsaglalasertsgsttlpfdf
sileftavs

Timeline for d1xdua2:

• d1xdua2 is new in SCOP 1.71
  
• d1xdua2 appears in SCOP 1.73
  
• d1xdua2 appears in the current release, SCOPe 2.08