SCOPe 2.06: Domain d1xd1a1: 1xd1 A:404-496

Lineage for d1xd1a1 (1xd1 A:404-496)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.71: Glycosyl hydrolase domain [51010] (1 superfamily)
   folded sheet; greek-key

4. Superfamily b.71.1: Glycosyl hydrolase domain [51011] (6 families)
   this domain is C-terminal to the catalytic beta/alpha barrel domain

5. Family b.71.1.1: alpha-Amylases, C-terminal beta-sheet domain [51012] (22 proteins)
   this domain follows the catalytic beta/alpha barrel domain

6. Protein Animal alpha-amylase [51024] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [51026] (53 PDB entries)
   Uniprot P04746 16-511 ! SQ 04746

8. Domain d1xd1a1: 1xd1 A:404-496 [115140]
   Other proteins in same PDB: d1xd1a2
   complexed with 6sa, ca, cl, nag

Details for d1xd1a1

PDB Entry: 1xd1, 2.2 Å

PDB Description: acarbose rearrangement mechanism implied by the kinetic and structural analysis of human pancreatic alpha-amylase in complex with analogues and their elongated counterparts

PDB Compounds: (A:) alpha-amylase

SCOPe Domain Sequences for d1xd1a1:

Sequence; same for both SEQRES and ATOM records:

>d1xd1a1 b.71.1.1 (A:404-496) Animal alpha-amylase {Human (Homo sapiens) [TaxId: 9606]}
qpftnwydngsnqvafgrgnrgfivfnnddwsfsltlqtglpagtycdvisgdkingnct
gikiyvsddgkahfsisnsaedpfiaihaeskl

Timeline for d1xd1a1:

• d1xd1a1 first appeared in SCOP 1.71
  
• d1xd1a1 appears in SCOPe 2.05
  
• d1xd1a1 appears in SCOPe 2.07
  
• d1xd1a1 appears in the current release, SCOPe 2.08