SCOP 1.71: Domain d1xcgf_: 1xcg F:

Lineage for d1xcgf_ (1xcg F:)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (23 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (45 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein RhoA [52612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52613] (12 PDB entries)

8. Domain d1xcgf_: 1xcg F: [115125]
   Other proteins in same PDB: d1xcga1, d1xcga2, d1xcge1, d1xcge2
   mutant

Details for d1xcgf_

PDB Entry: 1xcg, 2.5 Å

PDB Description: crystal structure of human rhoa in complex with dh/ph fragment of pdzrhogef

SCOP Domain Sequences for d1xcgf_:

Sequence; same for both SEQRES and ATOM records:

>d1xcgf_ c.37.1.8 (F:) RhoA {Human (Homo sapiens)}
airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq

Timeline for d1xcgf_:

• d1xcgf_ is new in SCOP 1.71
  
• d1xcgf_ appears in SCOP 1.73
  
• d1xcgf_ appears in the current release, SCOPe 2.08