SCOPe 2.08: Domain d1xcge1: 1xcg E:714-941

Lineage for d1xcge1 (1xcg E:714-941)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.87: DBL homology domain (DH-domain) [48064] (1 superfamily)
   multihelical; core: 5-helical bundle

4. Superfamily a.87.1: DBL homology domain (DH-domain) [48065] (2 families)
   automatically mapped to Pfam PF00621

5. Family a.87.1.1: DBL homology domain (DH-domain) [48066] (10 proteins)
   Pfam PF00621

6. Protein Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF [116957] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [116958] (5 PDB entries)
   Uniprot O15085 714-1081

8. Domain d1xcge1: 1xcg E:714-941 [115123]
   Other proteins in same PDB: d1xcga2, d1xcgb_, d1xcge2, d1xcgf_

Details for d1xcge1

PDB Entry: 1xcg, 2.5 Å

PDB Description: crystal structure of human rhoa in complex with dh/ph fragment of pdzrhogef

PDB Compounds: (E:) Rho guanine nucleotide exchange factor 11

SCOPe Domain Sequences for d1xcge1:

Sequence; same for both SEQRES and ATOM records:

>d1xcge1 a.87.1.1 (E:714-941) Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF {Human (Homo sapiens) [TaxId: 9606]}
qnwqhtvgkdvvagltqreidrqevinelfvteashlrtlrvldlifyqrmkkenlmpre
elarlfpnlpelieihnswceamkklreegpiikeisdlmlarfdgpareelqqvaaqfc
syqsialeliktkqrkesrfqlfmqeaeshpqcrrlqlrdliisemqrltkyplllesii
khteggtseheklcrardqcreilkyvneavkqtenrhrlegyqkrld

Timeline for d1xcge1:

• d1xcge1 first appeared in SCOP 1.71
  
• d1xcge1 appears in SCOPe 2.07