SCOPe 2.08: Domain d1x9na1: 1x9n A:262-533

Lineage for d1x9na1 (1x9n A:262-533)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.235: ATP-dependent DNA ligase DNA-binding domain [117017] (1 superfamily)
   multihelical; duplication: contains two intertwined structural repeats related by pseudo twofold symmetry

4. Superfamily a.235.1: ATP-dependent DNA ligase DNA-binding domain [117018] (1 family)

5. Family a.235.1.1: ATP-dependent DNA ligase DNA-binding domain [117019] (1 protein)
   Pfam PF04675

6. Protein DNA ligase I (LIG1) [117020] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [117021] (1 PDB entry)
   Uniprot P18858 262-901

8. Domain d1x9na1: 1x9n A:262-533 [115002]
   Other proteins in same PDB: d1x9na2, d1x9na3
   protein/DNA complex; complexed with amp

Details for d1x9na1

PDB Entry: 1x9n, 3 Å

PDB Description: Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA

PDB Compounds: (A:) DNA ligase I

SCOPe Domain Sequences for d1x9na1:

Sequence, based on SEQRES records:

>d1x9na1 a.235.1.1 (A:262-533) DNA ligase I (LIG1) {Human (Homo sapiens) [TaxId: 9606]}
dpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsarlrmvetlsnllrsvva
lsppdllpvlylslnhlgppqqglelgvgdgvllkavaqatgrqlesvraeaaekgdvgl
vaensrstqrlmlppppltasgvfskfrdiarltgsastakkidiikglfvacrhsearf
iarslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeqgm
ilkqtfcevpdldriipvllehglerlpehck

Sequence, based on observed residues (ATOM records):

>d1x9na1 a.235.1.1 (A:262-533) DNA ligase I (LIG1) {Human (Homo sapiens) [TaxId: 9606]}
dpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsarlrmvetlsnllrsvva
lsppdllpvlylslnhlgppqqglelgvgdgvllkavaqatgrqlesvraeaaekgdvgl
vaemlppppltasgvfskfrdiarltgsastakkidiikglfvacrhsearfiarslsgr
lrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeqgmilkqtfce
vpdldriipvllehglerlpehck

Timeline for d1x9na1:

• d1x9na1 first appeared in SCOP 1.71
  
• d1x9na1 appears in SCOPe 2.07