SCOPe 2.08: Domain d1x7gb_: 1x7g B:

Lineage for d1x7gb_ (1x7g B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein beta-keto acyl carrier protein reductase [51788] (8 species)

7. Species Streptomyces coelicolor [TaxId:1902] [117408] (8 PDB entries)
   Uniprot P16544 #SP

8. Domain d1x7gb_: 1x7g B: [114930]
   complexed with nap

Details for d1x7gb_

PDB Entry: 1x7g, 2.3 Å

PDB Description: Actinorhodin Polyketide Ketoreductase, act KR, with NADP bound

PDB Compounds: (B:) Putative ketoacyl reductase

SCOPe Domain Sequences for d1x7gb_:

Sequence, based on SEQRES records:

>d1x7gb_ c.2.1.2 (B:) beta-keto acyl carrier protein reductase {Streptomyces coelicolor [TaxId: 1902]}
matqdsevalvtgatsgigleiarrlgkeglrvfvcargeeglrttlkelreagveadgr
tcdvrsvpeiealvaavverygpvdvlvnnagrpgggataeladelwldvvetnltgvfr
vtkqvlkaggmlergtgrivniastggkqgvvhaapysaskhgvvgftkalglelartgi
tvnavcpgfvetpmaasvrehysdiwevsteeafdritarvpigryvqpsevaemvayli
gpgaaavtaqalnvcgglgny

Sequence, based on observed residues (ATOM records):

>d1x7gb_ c.2.1.2 (B:) beta-keto acyl carrier protein reductase {Streptomyces coelicolor [TaxId: 1902]}
matqdsevalvtgatsgigleiarrlgkeglrvfvcargeeglrttlkelreagveadgr
tcdvrsvpeiealvaavverygpvdvlvnnagrpgggataeladelwldvvetnltgvfr
vtkqvlkaggmlergtgrivniastggkqgvvhaapysaskhgvvgftkalglelartgi
tvnavcpgfvetpmaasvrefdritarvpigryvqpsevaemvayligpgaaavtaqaln
vcgglgny

Timeline for d1x7gb_:

• d1x7gb_ first appeared in SCOP 1.71
  
• d1x7gb_ appears in SCOPe 2.07