Lineage for d1wt2a_ (1wt2 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2133075Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest
  4. 2133076Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families) (S)
  5. 2133477Family c.68.1.9: alpha-1,3-galactosyltransferase-like [64131] (4 protein domains)
    automatically mapped to Pfam PF03414
  6. 2133522Protein Glycosyltransferase A catalytic domain [75276] (1 species)
    involved in blood group antigen biosynthesis
  7. 2133523Species Human (Homo sapiens) [TaxId:9606] [75277] (53 PDB entries)
    Uniprot P16442 64-345
  8. 2133565Domain d1wt2a_: 1wt2 A: [114871]
    complexed with hg, udp; mutant

Details for d1wt2a_

PDB Entry: 1wt2 (more details), 1.9 Å

PDB Description: Mutant human ABO(H) blood group glycosyltransferase A with bound UDP and inhibitor
PDB Compounds: (A:) Histo-blood group ABO system transferase

SCOPe Domain Sequences for d1wt2a_:

Sequence, based on SEQRES records: (download)

>d1wt2a_ c.68.1.9 (A:) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
mvslprmvypqskvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvfa
ikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevraykrwq
dvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpgfygssre
aftyerrpqsqayipkdegdfyylggffggsvqevqrltrachqammvdqangieavwhd
eshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavp

Sequence, based on observed residues (ATOM records): (download)

>d1wt2a_ c.68.1.9 (A:) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
mvslprmvypqskvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvfa
ikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevcerrfls
evdylvcvdvdmefrdhvgveiltplfgtlhpgfygssreaftyerrpqsqayipkdegd
fyylggffggsvqevqrltrachqammvdqangieavwhdeshlnkyllrhkptkvlspe
ylwdqqllgwpavlrklrftavp

SCOPe Domain Coordinates for d1wt2a_:

Click to download the PDB-style file with coordinates for d1wt2a_.
(The format of our PDB-style files is described here.)

Timeline for d1wt2a_: