Lineage for d1wcha_ (1wch A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2116263Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2116264Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2116365Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 protein domains)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 2116558Protein Tyrosine-protein phosphatase, non-receptor type 13 (PTPL1) [117581] (1 species)
  7. 2116559Species Human (Homo sapiens) [TaxId:9606] [117582] (1 PDB entry)
    Uniprot Q12923 2170-2477 # structure of a PDZ domain (1361-1456) is also known (50169)
  8. 2116560Domain d1wcha_: 1wch A: [114508]
    complexed with po4

Details for d1wcha_

PDB Entry: 1wch (more details), 1.85 Å

PDB Description: crystal structure of ptpl1 human tyrosine phosphatase mutated in colorectal cancer - evidence for a second phosphotyrosine substrate recognition pocket
PDB Compounds: (A:) protein tyrosine phosphatase, non-receptor type 13

SCOPe Domain Sequences for d1wcha_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1wcha_ c.45.1.2 (A:) Tyrosine-protein phosphatase, non-receptor type 13 (PTPL1) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1wcha_:

Click to download the PDB-style file with coordinates for d1wcha_.
(The format of our PDB-style files is described here.)

Timeline for d1wcha_: