SCOPe 2.02: Domain d1w8aa_: 1w8a A:

Lineage for d1w8aa_ (1w8a A:)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.10: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046] (3 superfamilies)
   2 curved layers, a/b; parallel beta-sheet; order 1234...N; there are sequence similarities between different superfamilies

4. Superfamily c.10.2: L domain-like [52058] (9 families)
   less regular structure consisting of variable repeats

5. Family c.10.2.7: Ngr ectodomain-like [75142] (6 proteins)
   this is a repeat family; one repeat unit is 1xwd C:97-122 found in domain

6. Protein Slit [117461] (1 species)

7. Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [117462] (1 PDB entry)
   Uniprot P24014 542-733

8. Domain d1w8aa_: 1w8a A: [114363]
   3rd LRR domain

Details for d1w8aa_

PDB Entry: 1w8a, 2.8 Å

PDB Description: third lrr domain of drosophila slit

PDB Compounds: (A:) slit protein

SCOPe Domain Sequences for d1w8aa_:

Sequence, based on SEQRES records:

>d1w8aa_ c.10.2.7 (A:) Slit {Fruit fly (Drosophila melanogaster) [TaxId: 7227]}
dcpamchcegttvdctgrglkeiprdiplhttelllndnelgrissdglfgrlphlvkle
lkrnqltgiepnafegashiqelqlgenkikeisnkmflglhqlktlnlydnqiscvmpg
sfehlnsltslnlasnpfncnchlawfaewlrkkslnggaarcgapskvrdvqikdlphs
efkcssensegc

Sequence, based on observed residues (ATOM records):

>d1w8aa_ c.10.2.7 (A:) Slit {Fruit fly (Drosophila melanogaster) [TaxId: 7227]}
dcpamchcegttvdctgrglkeiprdiplhttelllndnelgrissdglfgrlphlvkle
lkrnqltgiepnafegashiqelqlgenkikeisnkmflglhqlktlnlydnqiscvmpg
sfehlnsltslnlasnpfncnchlawfaewlrkkslnggaarcgapskvrdvqikdlphs
efkcssegc

Timeline for d1w8aa_:

• d1w8aa_ first appeared in SCOP 1.71
  
• d1w8aa_ appears in SCOPe 2.01
  
• d1w8aa_ appears in SCOPe 2.03
  
• d1w8aa_ appears in the current release, SCOPe 2.08